![]() ![]() But the fact is that many of the claims made about things behind this veil have empirically observable consequences and that makes them scientifically testable. Then they insist that there are special people who can see – if only dimly – through this veil. Behind the veil they will put angels, aliens, psychic powers, God, ghosts and so on. But what some people do to protect their beliefs is to draw a veil across reality and say, “you scientists can go up to the veil and apply your empirical methods this far, but no further”. There probably are questions that science cannot answer. When you hear that, alarm bells should go off.īut even scientists admit that they can’t explain everything. You, Mr Clever Dick Scientist, are guilty of scientism, of assuming science can answer every question.” This is often followed by that quote from Shakespeare’s Hamlet: “There are more things in heaven and earth, Horatio, than are dreamt of in your philosophy”. They might say something like: “Ah, but this is beyond the ability of science and reason to decide. This involves appealing to mystery to get out of intellectual hot water when someone is, say, propounding paranormal beliefs. Tell me about one of them – “playing the mystery card”? You identify some strategies people use to defend black hole beliefs. They merely appear so to those trapped inside. Beliefs at the core of intellectual black holes, however, aren’t reasonable. That’s because these beliefs are genuinely reasonable. We are powerfully wedded to this but that doesn’t make it an intellectual black hole. There’s a belief system about water to which we all sign up: it freezes at 0 ☌ and boils at 100 ☌. As you approach them, you need to be on your guard because if you get sucked in, it can be extremely difficult to think your way clear again.īut isn’t one person’s claptrap another’s truth? ![]() Belief in homeopathy, psychic powers, alien abductions – these are examples of intellectual black holes. Intellectual black holes are belief systems that draw people in and hold them captive so they become willing slaves of claptrap. You describe your new book, Believing Bullshit, as a guide to avoid getting sucked into “intellectual black holes”. In reality, the gravitational pull of a black hole is the same of that for a regular star-just a lot stronger.How do people defend their beliefs in bizarre conspiracy theories or the power of crystals? Philosopher Stephen Law has tips for spotting their strategies Black holes get a bad reputation for sucking in their surroundings, like some sort of cosmic vacuum cleaner. So, if we can’t agree, what do we think happens to you? Black holes don’t suckįirst, let’s clear up a common misconception. ![]() You, as the faller, would experience a reality very different from what I, as an observer from the outside, would see. The answer is surprising because you get a different one depending on whom you ask. But what would happen to you if you were to find yourself falling into a black hole? Thanks to Einstein’s theory of general relativity, a framework that helps us understand how space and time behave in the presence of strong gravity, we can predict the specifics of what would happen to us without having to go through it ourselves. ![]() If massless photons cannot escape the clutches of a black hole, then certainly neither could we. The stellar core can then implode in the production of a supernova or, as is the case for more massive stars, collapse to then form a black hole. Once a star runs out of fuel to burn, and thus can no longer support itself via radiation pressure, the layers of metals fused up to that point will all come crashing down towards the center. As we discussed in a previous episode, black holes can form as a result of stellar death. Black holes are regions of space where the gravity is so thick that not even light can force its way out. ![]()
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![]() It has received three Pulitzer Prizes and many other awards over the years for its coverage of news, music, art, theater, film, politics, activism and more.īob Dylan was the cover star of its final issue, published in September 2017. The alternative New York City subreddit Press J to jump to the feed. We are proud to be able to revive both the digital and print editions of this paper.” The Village Voice Returns, and It’s ‘Very Village Voice-y’ : newyorkcity 97.6k members in the newyorkcity community. “For more than six decades, it was the heart of New York City and the voice of the community it served. The title “represents one of the most iconic papers in our nation and the very best of local media,” Calle enthused in a statement. The Village Voice was the country’s first alternative newsweekly, founded in 1955 by a group that included legendary writer Norman Mailer. “I think a lot of people will be hungry for this and I’m superoptimistic,” Calle told The Times. ![]() ![]() Also, the New York Times quotes Street Media CEO Brian Calle as saying the Village Voice will include a print periodical, expected to be published each quarter. In the years since, its website and social channels have been refreshed with articles posted from the vault.įrom next year, the site will get a revamp with fresh content. Village Voice Writers, Editors Recall Their First Story For the Defunct PublicationĪt the time of its closure, Barbey said the venerable title had bore the brunt of “the increasingly harsh economic realities” facing those creating journalism. ![]() ![]() ![]() In 2009, del Castillo was appointed Ambassador for the Mexican Commission on Human Rights and the following year she helped launch the Blue Heart Campaign in order to raise awareness and fight human trafficking. In November 2007, Del Castillo was named one of the "Stars of the Year" and in 2011 one of the "25 most influential women" and "50 most beautiful" by People en Español magazine. She also starred in a number of independent movies, include The Black Pimpernel (2007) and Julia alongside Tilda Swinton. ![]() The film grossed $23.3 million against $1.7 million budget. In 2007, she went to star in the drama film Under the Same Moon directed by Patricia Riggen. ![]() In 2006, Del Castillo starred in the film Bordertown, which became her first role in Hollywood. In 2005, she starred alongside Demián Bichir in the romantic comedy film American Visa. In 20, she embarked on an international tour alongside Argentine actor Saul Lisazo with the play Cartas de Amor ( Love Letters). In 2009, she had a recurring role in the Showtime dark comedy-drama Weeds playing Pilar Zuazo, a powerful woman in Mexican politics. In 2003, she made her American television debut playing a recurring role in the PBS drama series American Family starring Edward James Olmos and Sônia Braga. In early 2000s, Del Castillo played the leading roles in telenovelas Ramona (2000), El derecho de nacer (2001) and Bajo la misma piel (2003-2004). In 1995 she appeared in the music video " Fuego de Noche, Nieve de Día" by Ricky Martin. Her other leading roles in 1990s was in Azul (1996), long-running Alguna vez tendremos alas (1997), and La mentira. The following year, she went to star in Mágica juventud. She became well known in 1991 when she starred as Leticia in Muchachitas, a telenovela airing in several Latin American countries. Del Castillo made her Hollywood debut playing a female leading role in the 2007 drama film Under the Same Moon and later appeared in supporting roles in films No Good Deed (2014), The 33 (2015), El Chicano (2019), and Bad Boys for Life (2020).ĭel Castillo made her acting debut in 1978 when she took part in a film called The Last Escape. In 2017, she went to star in the Netflix political drama series Ingobernable playing First Lady of Mexico Emilia Urquiza. In 2011, del Castillo earned worldwide recognition for playing the lead role in the Telemundo series La Reina del Sur. Afterwards, she continued her career in film and television in Latin America, playing the leading roles in telenovelas, including Alguna vez tendremos alas (1997), La Mentira (1998), Ramona (2000), and Bajo la misma piel (2003–04). At the age of 19, del Castillo became known for her lead role in the telenovela Muchachitas for Televisa in 1991. Wishing we looked this glam getting ready in the morning, tbh.Kate del Castillo Negrete Trillo ( Spanish pronunciation: ) is a Mexican-American actress. Scroll through and you'll see two more snaps from Katy's dressing room, with the singer posing alongside her hairstylist Jesus Guerrero and makeup artist Michael Anthony. ![]() When a pic's that good, you want everyone to see it, right? Just in case anyone missed out on the grid pic, Katy followed up by sharing the post to her Instagram Story too. The singer added the caption, "let it burn baby □" in response to the sign, before adding "#WIG" - a nod to her new song 'When I'm Gone' with Alesso. A post shared by KATY PERRY another glance at the photo and you'll see Katy is posing next to a sign reading, "Do not hose down," which is presumably a reference to how fire she looks. ![]() ![]() ![]() Substantial progress has been made in elucidating the pathological mechanisms underlying PD, but the failure of recent clinical trials targeting established pathological pathways suggests that current drug discovery strategies remain inadequate 15. While variants in many genes including LRRK2 11, GBA 12, and SNCA 13 have been associated with disease risk, over 90% of cases are sporadic, caused by unknown genetic and environmental factors 14. Parkinson’s disease (PD) is the second most prevalent progressive neurodegenerative disease, affecting 2–3% of individuals over the age of 65 10. Several studies have applied AI to large datasets to uncover population-based disease phenotypes and biomarkers, but the power of these studies thus far has been limited by small cohort sizes 6, 7 and non-physiological cellular perturbations 8, 9. Applying similar unbiased approaches to large, high-quality datasets using methods such as high-content imaging is a powerful strategy to capture novel patient- or disease-specific phenotypic patterns. ![]() Recent advancements in artificial intelligence (AI) and deep learning–based analysis offer the potential to accelerate therapeutic discovery by distinguishing drug-induced cellular phenotypes 2, elucidating mechanisms of action 3, and gaining insights into drug repurposing 4, 5. The increasing availability of patient cells through biobanking and induced pluripotent stem cell (iPSC) models presents an excellent opportunity for cell-based drug discovery, but in the absence of reliable drug targets, new methods to discover unbiased, quantitative cellular phenotypes are still needed. Lastly, our models confidently separate LRRK2 and sporadic Parkinson’s disease lines from healthy controls (receiver operating characteristic area under curve 0.79 (0.08 standard deviation)), supporting the capacity of this platform for complex disease modeling and drug screening applications.Ī major challenge in discovering effective therapies for complex diseases is defining robust disease phenotypes amenable to high-throughput drug screens 1. Our platform’s robustness and sensitivity allow the detection of individual-specific variation with high fidelity across batches and plate layouts. We use fixed weights from a convolutional deep neural network trained on ImageNet to generate deep embeddings from each image and train machine learning models to detect morphological disease phenotypes. We applied this platform to primary fibroblasts from 91 Parkinson’s disease patients and matched healthy controls, creating the largest publicly available Cell Painting image dataset to date at 48 terabytes. We present an unbiased phenotypic profiling platform that combines automated cell culture, high-content imaging, Cell Painting, and deep learning. Nature Communications volume 13, Article number: 1590 ( 2022)ĭrug discovery for diseases such as Parkinson’s disease are impeded by the lack of screenable cellular phenotypes. Integrating deep learning and unbiased automated high-content screening to identify complex disease signatures in human fibroblasts ![]() ![]() Then I'm in a game called The Gallery: Six Elements, which puts me in a dungeon. This is by far the most impressive thing about the demo I'm able to pick up an object, toss it in the air, and catch it. If you've played with a Wii remote or a PlayStation Move controller, you basically understand how this works, though these are much more accurate. Not pictured are the highly impractical two cameras high up in opposite corners of the room that are tracking the controllers and the headset. The anxious men slip the phallic controllers you can see me holding in the picture above into my hands. Turn on your TV and get close enough that your nose touches the screen and you can see the gaps between the pixels that make up the image. Inside, through two lenses, I look at a screen that I am sure at some point was going to be an HTC smartphone. We've added a bonus fart to our wheel called "Fart-O-Rater".I step into a small empty room where two anxious men who have to give dozens of demos a day are already running late, so they quickly slap the device on my head. * Celebrities - Sorry Kanye, you didn't make the cuts. * Food - You can't have dessert until you play all these farts. * Bands - The bands on the runs with these farts. * Movies - In a world without gas… this is a land that prays for a hero. ![]() * Fart Wars - May the Flatulence Be With You * Presidential - Joe, Kamala, Bernie, Hillary, & Donald let em rip! * Jurassic - Ever wonder what a Dinosaur fart sounds like?. IFart includes EIGHT of our funniest Fart Packs, each pack contains up to 10 fresh cuts for your enjoyment. just hit the BLAST button and let the healing begin. If only there was an internationally recognized sound that alleviates stress, brings laughter, lowers blood pressure, clears a room, helps bring peace to the middle east and is enjoyed by both Democrats and Republicans. You can also record and rename multiple farts which are stored in the FAVES list. Using our FAVES feature you can create a playlist of your fave farts for easy access. Using iFart’s "Record-A-Fart" feature you can now make audible memories for a lifetime and play them for friends and family. The birth of a child, a stunning sunset, bigfoot, and of course, the after effects of a triple burrito lunch. There are special moments in life that just have to be captured on your phone to be believed. When the Sneak Attack goes off, slip away or take out the bad guys when they reach for their noses. Then place your phone in a strategic location and move silently away. Simply pull out your phone, choose a sound effect and set the timer up to 30 seconds. Bad guys are closing in on you, but if you only had a distraction, you could escape. Let's say that you're in a warehouse gun battle. The sneak attack function can literally save your life. Most criminals know how to lie, but "it wasn't me" isn't going to work with iFart.Ĭall the authorities and send these phone stealing scumbags off to the gas chamber. ![]() Phones and pdas are stolen on a daily basis, but if you are using iFart's advanced security system you can stop criminals right in their tracks.Īnd when thieves try to snatch your phone, they'll be in for a shock when they're blasted by your chosen sound effect. Here are just a few of the useful, signature features of iFart®. The App has been completely recoded and rebuilt for 2021. We can’t even tell you how much time it spent farting around at #2. It continued to linger in the Top Ten for over a year! It blasted to #1 on Christmas Day of that year and clinged to number one for weeks. IFart® took the app world by storm in 2008. The definitive Fart Sounds app on iTunes.įeatured on The Daily Show with Jon Stewart, The Today Show and many others, iFart® is considered the most infamous app of all time.Īlso seen in the Wall Street Journal, USA Today,, MacDailyNews, MacForums, The New York Times, Barron's, Motley Fool, Gizmodo, Venture Beat, Ars Technica, CNET News,, Forbes, The UK Register, Information Week, and dozens of publications all over the world! You’ve discovered the Original and World Famous iFart® App. ![]() ![]() ![]() The largest set element for Ovo is the trampowall located at the back of the stage. ![]() The giant egg at the beginning of Ovo is a symbol of fertility and is a nod to The Monolith in the Stanley Kubrick movie 2001: A Space Odyssey. The acrobatic structure used during the Slackwire Act is at a 45° degree angle. The middle of the stage is able to be raised and rotated. The stage floor contains 225 panels and with the exception of the Spider’s Web, there are no straight lines found anywhere on set. Set designer Gringo Cardia was inspired by the nests and colonies of various insects when designing the stage for Ovo. In 2016 while converting to an arena format, Cirque du Soleil teamed up with their video and scenographic design subdivision 4U2C to improve on the show's design, lighting, technical aspects, special effects, and projections. We behave as change agents to reach our ultimate goal of making a better world with our actions and our productions." It is a principle that guides us with both our employees and our customers. Cirque du Soleil believes in equality for all. The new HB2 legislation passed in North Carolina is an important regression to ensuring human rights for all. In a press release on Facebook, the company stated: "Cirque du Soleil strongly believes in diversity and equality for every individual and is opposed to discrimination in any form. On April 2015, Cirque du Soleil announced the cancellation of Ovo and Toruk: The First Flight's performances in North Carolina due to the passing of The Public Facilities Privacy & Security Act or HB2 by North Carolina Governor Pat McCrory. Performances resumed on May 3rd to May 15th. This was due to the Ohio River over flooding with heavy rains. In late April 2011, Ovo canceled performances from April 28th through May 1st in Coney Island, Cincinnati, Ohio. ![]() ![]() ADP has adopted a rigorous set of principles and processes to govern its use of these newer technologies. We embrace innovative new tools – including artificial intelligence and machine learning solutions - to address the critical needs of our clients and associates. Inspiring Innovation is one of ADP’s core values. Learn more about Privacy at ADP, including understanding the steps that we’ve taken to protect personal data globally. At ADP, security is integral to our products, our business processes and our infrastructure. Today’s digital landscape means limitless possibilities, and also complex security risks and threats. Learn more about the senior executives who are leading ADP’s business. We have been recognized by esteemed organizations for the value we bring to our clients, our associates and the global community. At ADP, we say that we’re Always Designing for People, starting with our own.Īt ADP, we are committed to unlocking potential - not only in our clients and their businesses, but in our people, our communities and society as a whole. We’re reimagining what it means to work, and doing so in profound ways. See All LocationsĪDP hires in over 26 countries around the world for a variety of amazing careers. Whether you operate in multiple countries or just one, we can provide local expertise to support your global workforce strategy. ![]() We provide payroll, global HCM and outsourcing services in more than 140 countries. See What Others SayĪDP helps organizations of all types and sizes unlock their potential. View Demosĭon’t just take our word for it. Overviewĭiscover how easy and intuitive it is to use our solutions. View BlogĪccess the definitive source for exclusive data-driven insights on today’s working world. Read the latest news, stories, insights and tips to help you ignite the power of your people. See Webinars & Eventsĭon’t take our word for it. See All ToolsĪttend webinars or find out where and when we can connect at in-person events. View Resourcesįind payroll and retirement calculators, plus tax and compliance resources. Tap into a wealth of knowledge designed to simplify complex tasks and encourage strategic decisions across key functions. Resources Overviewĭiscover the latest Today at Work insights from the ADP Research Instituteĭiscover a wealth of knowledge to help you tackle payroll, HR and benefits, and compliance. Take your organization to the next level with tools and resources that help you work smarter, regardless of your business’s size and goals. Learn how we can make a difference by joining forces to improve the success of the clients we share. Learn how we can tackle your industry demands together. You face specific challenges that require solutions based on experience. Small, midsized or large, your business has unique needs, from technology to support and everything in between. See how we help organizations like yours with a wider range of payroll and HR options than any other provider. Marketplace OverviewĬomprehensive payroll and HR software solutions. ![]() Our online store for HR apps and more for customers, partners and developers. Quickly connect ADP solutions to popular software, ERPs and other HR systems. ![]() Simplify and unify your HCM compliance processes. Benefits Overviewįrom best practices to advice and HR consulting.įocus on what matters most by outsourcing payroll and HR tasks, or join our PEO. Talent OverviewĮmployee benefits, flexible administration, business insurance, and retirement plans. For advanced capabilities, workforce management adds optimized scheduling, labor forecasting/budgeting, attendance policy, leave case management and more.įrom recruitment to retirement, getting the very best out of your people. Manage labor costs and compliance with easy time & attendance tools. Payroll OverviewĬompare Packages Find the package that's right for your business. Explore our full range of payroll and HR services, products, integrations and apps for businesses of all sizes and industries.įast, easy, accurate payroll and tax, so you can save time and money. ![]() ![]() ![]() Print PDFsĪdobe Reader makes it incredibly simple to print PDF documents. Adobe Reader is the most popular program for viewing PDFs, as it is free on various devices. PDFs are a type of file that can be created by various software programs and are often used for documents that need to be printed or shared electronically. Open and view PDFsĪdobe Reader allows you to open and view PDF documents. Adobe Reader for Windows FeaturesĪdobe Reader for Windows offers a comprehensive set of features designed to make it easier to open, view and manage PDF documents on Windows devices. You can also enable additional layers of protection like data encryption or redaction features to black out confidential information in the document itself. For instance, you can control who can view and edit a document by setting passwords or requiring digital signatures before accessing certain sections. The program also supports different languages, so you can easily change the menus’ language, depending on your preference.Īdobe Reader for Windows also offers advanced security features that give you peace of mind when sharing sensitive information and protecting it from unauthorized access. The user interface is simple and intuitive, allowing even new users to quickly get the hang of using the program. It has a feature-rich set of tools designed to make it easy to select the text, comment on content, and share documents with others. With Adobe Reader, you can easily access and view PDFs on your Windows device. Adobe Reader for Windows is an industry-leading software designed to help you easily open and read PDF documents. ![]() ![]() I wish the price was a bit less, but I really havent had any problems with version 7.1 or 7.1.2 it was 7.1.1 that almost ruined the application. I find it quite easy to use it seems to have the best feel of the screenwriting software Ive tried so far. It also sometimes wouldnt refresh correctly, leaving deleted text apparently on it even though it was deleted.įortunately, I contacted the support and got something that returned it to 7.1, so I enjoyed using it again.Īm I the only one that has a problem with this Whats the point of releasing a buggy version, then (after a while, that is, not quickly enough) releasing a version that fixes the problems, only to only let SOME of the users who have the buggy version update.īest advice I can give is probably to contact the technical support via the web and ask for help. It wouldnt export in some of the formats I wanted without crashing, if I tried scrolling down using the cursor it left these weird lines behind (not in the text itself, but on the document). Navigate to where you just downloaded the Farmland - Tagger Testscript file. Given that some people had complained about how it was buggy, I was a bit nervous about it, but it caused very few problems for me. Final Draft ® 12 is here Used by 95 of film and television productions. However, instead of installing it by dragging its icon to the Application folder, uninstalling Final Draft Tagger 2.1.1.3.0 may need you to do more than a simple drag-and-drop to the Trash. Tagger Tagger Answer NOTE: Tagger and Tagger 2 are no longer supported in any way by Final Draft (a Cast & Crew Company). ![]() While it comes at a price, this writing software provides all the tools needed to plan out and keep track of your script, while remaining relatively easy to learn.įinal Draft automatically paginates and formats your script to industry standards as you write. Final Draft Tagger 2.1.1.3.0 is a third party application that provides additional functionality to OS X system and enjoys a popularity among Mac users. Scripts can be saved in a proprietary format or exported as PDFs. Download and install Tagger (NOTE that Tagger is obsolete and is no longer supported. Other features of note include script locking to prevent edits to specific parts, character tracking, revision support, title page creation, a names database, and a format assistant. The package you are about to download is authentic and was not repacked or modified in any way by us. ![]() Each download we provide is subject to periodical scanning, but we strongly recommend you to check the package for viruses on your side before running the installation. These articles are from some of the best screenwriters and teachers around the world. You will also receive several free screenwriting articles and Final Draft tutorials over the next few weeks. The app features an alternative view where your script is broken down into separate index cards, each containing a scene.Įach scene can have a title, summary, and a color code, which will not appear on the script, itself, but may provide valuable context while writing. The download version of Final Draft is 12.05. In the next few minutes you will receive an email with your trial customer number and a link to download and install Final Draft 12. Final Draft Tagger Software Provides All. ![]() ![]()
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